Molecular tests

• Qualitative detection of HCV RNA (PCR)

Cut-off: 100 copies/ml

= 50 IU/ml

Not 100% sensitive Intermittent viremia

Inappropriate handle of

specimen (plasma)

97-99% specific Contaminations

Indications Blood donors

HCV+ve, Riba+ve or indet

Acute hepatitis

Cryo +

Immunosuppressed patients

Hemodialysis

Monitoring of ? efficacy

Childs born from HCV+ve mothers

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