Treatment of hepatitis CImpact on the virus, the quality of life and the natural history

6/10/2002

Table of Contents Treatment of hepatitis CImpact on the virus, the quality of life and the natural history Minimal criteria for treatment chronic hepatitis C (NIH 1997, EASL, 1999) Definitions of response Definitions of response Treatment of chronic hepatitis CThe past Treatment of chronic hepatitis CThe present ET and Sustained Virological Response PPT Slide PPT Slide EASL Consensus Conference, Feb 1999 Treatment of chronic hepatitis CThe near future PEGINTRON + RIBAVIRINSustained Virological Response Manns et al., Lancet 358, 958, 2001 PEGASYS + RIBAVIRINFried et al., DDW, May 2001 PEGASYS + RIBAVIRINSVR by genotype Fried et al., DDW, May 2001 Treatment of chronic hepatitis CThe (far) future Health-related quality of life (HRQL) Effect chronic hepatitis C on HRQLBonkovsky et al., Hepatology 29, 267, 1999 Effect treatment chronic hepatitis C on HRQLBonkovsky et al., Hepatology 29, 267, 1999 Effect of treatment on the natural history of chronic hepatitis C Therapy of chronic hepatitis C Cost-effectiveness analyses Guidelines acceptability cost-effectiveness ratio ($/QALY) Therapy of chronic hepatitis CMarginal cost-effectiveness ratio ($,€/QALY saved) Treatment of acute hepatitis C Conclusions (1) Conclusions (2)

Author: P. Michielsen, R. Brenard, H. Reynaert